Description
Transient receptor potential cation channel, subfamily C, member 7, also known as TRP7, is a human gene encoding a protein named TRPC7. It is the most abundantly expressed long TRPC in peripheral blood and in some blood cell lines. TRPC7 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. It is activated by oxidative stress and confers susceptibility to cell death